个人简介

孙胜香，博士。2019年毕业于华东师范大学生命科学学院，2019-2021年留华东师范大学进行博士后研究，2021-2024年在美国Washington University School of Medicine进行博士后深造。从事代谢与肠肝轴稳态调控，以及炎症性肠病的发病机制与治疗策略等研究。以第一作者在Science Immunology、Science Translational Medicine、Gastroenterology、BBA等期刊发表论文著作。

联系方式：shengxiang@henu.edu.cn

代表性论著：

1. Sun SX, Hodel M, Wang X, Vicente JD, Haritunians T, Debebe A, Ma CQ, et. al. Macrophage LRRK2 hyperactivity impairs autophagy and induces Paneth cell dysfunction. Science Immunology. 9,eadi7907 (2024). DOI:10.1126/sciimmunol.adi7907
2. Malique A*, Sun SX*, Chandwe K, Amadi B, Haritunians T, Jain U, Muegge BD, et.al. NAD+ precursors and bile acid sequestration treat preclinical refractory environmental enteric dysfunction. Science Translational Medicine. 2024 Jan 3;16(728):eabq4145. PMID: 38170788. （*co-first author）
3. Sun SX, Wu JL, Lv HB, Zhang HY, Zhang J, Limbu SM, Qiao F, Chen LQ, Yang Y, Zhang ML, Du ZY. Environmental estrogen exposure converts lipid metabolism in male fish to a female pattern mediated by AMPK and mTOR signaling pathways. Journal of Hazardous Materials. 2020 Jul 15;394:122537. PubMed PMID: 32203715.
4. Sun SX, Frein J, Foster A, Ma CQ, Liu TC et al. Hepatocyte-specific deletions of autophagy-initiating genes result in pronounced hepatomegaly and pathology. Gastroenterology. 2024 May; 166(5): S-1562. DOI:10.1016/s0016-5085(24)04046-0. (AASLD Abstract)
5. Sun SX, Liu YC, Limbu SM, Li DL, Chen LQ, Zhang ML, Yin Z, Du ZY. Vitellogenin 1 is essential for fish reproduction by transporting DHA-containing phosphatidylcholine from liver to ovary. BBA Molecular and Cell Biology of Lipids. 2023 Apr;1868(4):159289. PMID: 36708962.
6. Sun SX, Hu CT, Qiao F, Chen LQ, Zhang ML, Du ZY. High dissolved oxygen exacerbates ammonia toxicity with sex-dependent manner in zebrafish. Comparative Biochemistry and Physiology Part C. 2023 Apr;266:109549. PMID: 36690240. 
7. Sun SX, Zhang YN, Lu DL, Wang WL, Limbu SM, Chen LQ, Zhang ML, Du ZY. Concentration-dependent effects of 17β-estradiol and bisphenol A on lipid deposition, inflammation and antioxidant response in male zebrafish (Danio rerio). Chemosphere. 2019 Dec;237:124422. PubMed PMID: 31352104.
8. Sun SX, Hua XM, Deng YY, Zhang YN, Li JM, Wu Z, Limbu SM, Lu DS, Yin HW, Wang GQ, Waagbø R, Frøyland L, Zhang ML, Du ZY. Tracking pollutants in dietary fish oil: From ocean to table. Environmental Pollution. 2018 Sep;240:733-744. PubMed PMID: 29778059.
9. Balasubramanian I, Bandyopadhyay S, Flores J, Bianchi-Smak J, Lin X, Liu H, Sun SX, Golovchenko NB, et.al. Infection and inflammation stimulate expansion of a CD74+ Paneth cell subset to regulate disease progression. The EMBO Journal. 2023 Nov 2;42(21):e113975. PMID: 37718683.
10. Hung CT, Ma C, Panda SK, Trsan T, Hodel M, Frein J, Foster A, Sun SX, Wu HT, et.al.  Western diet reduces small intestinal intraepithelial lymphocytes via FXR-Interferon pathway. Mucosal Immunology. 2024 Jul 9:S1933-0219(24)00067-9. PMID: 38992433.
11. Lu DL, Ma Q, Sun SX, Zhang H, Chen LQ, Zhang ML, Du ZY. Reduced oxidative stress increases acute cold stress tolerance in zebrafish. Comparative Biochemistry and Physiology Part A. 2019 Sep;235:166-173. PubMed PMID: 31220619.
12. Limbu SM, Zhou L, Sun SX, Zhang ML, Du ZY. Chronic exposure to low environmental concentrations and legal aquaculture doses of antibiotics cause systemic adverse effects in Nile tilapia and provoke differential human health risk. Environment International. 2018 Jun;115:205-219. PubMed PMID: 29604537.